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Neonatal polycythaemia: effect of partial dilutional exchange transfusion with human albumin on whol |
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Neonatal polycythaemia: effect of
partial dilutional exchange transfusion with human albumin on whole blood
viscosity.
Levy I, Merlob P, Ashkenazi S,
Reisner SH.
Eur J Pediatr 1990
Feb;149(5):354-5
Haematocrit (HCT) and viscosity of whole blood were
measured in ten polycythaemic hyperviscous newborn infants both before and after
dilutional partial exchange transfusion with 5% albumin. This was performed in
order to evaluate the effect on the lowering of HCT and whole blood viscosity.
Mean umbilical HCT values decreased from 68.7% before, to 54.4% post
transfusion. This decrease in HCT and viscosity was highly significant (P less
than 0.001). Safety and lack of complications make human albumin solution
superior to human plasma for exchange transfusion in neonatal
polycythaemia.
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