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Hypoalbuminemia is a predictor of delayed postoperative bowel function and poor surgical outcomes in |
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Hypoalbuminemia is a predictor of delayed
postoperative bowel function and poor surgical outcomes in right-sided
colon cancer patients.
Asia Pac J Clin Nutr. 2007;16(2):213-7.
Lohsiriwat V, Chinswangwatanakul V, LLohsiriwat S, Akaraviputh T, Boonnuch W, Methasade A, Lohsiriwat D.Department
of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University,
Prannok Rd, Bangkoknoi, Bangkok 10700, Thailand.
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Purpose:
To determine the relationship between preoperative serum albumin and
postoperative bowel function as well as surgical outcomes in
right-sided colon cancer patients.
Methods: This retrospective study in
a university hospital included 84 patients who underwent elective right
hemicolectomy for adenocarcinoma of the right-sided colon between
January 2004 and December 2005. The patients had a preoperative serum
albumin assessment. Serum albumin less than 3.5 g/dL was regarded as
hypoalbuminemia. Postoperative outcomes were classified into mortality,
morbidity (infectious and noninfectious complications), time to first
bowel movement, time to resume normal diet, and hospital stay. Results:
Forty males (48%) and forty-four females (52%) with a mean age of 64
(range, 27-89) years were included. Forty-eight patients (57%) had
hypoalbuminemia. No 30-day postoperative mortality occurred. All 14
postoperative complications occurred in hypoalbuminemic cases.
Therefore, 29% of the hypoalbuminemics had complications whereas none
occurred in nonhypoalbuminemics (p=0.001). In univariate analysis,
hypoalbuminemia and postoperative complications were the risk factors
for delayed postoperative recovery of bowel function and prolonged
length of hospital stay. In multivariate analysis, hypoalbuminemia was
the significant risk factor for postoperative complications
(p<0.001) and delayed time to first bowel movement (p=0.018) whereas
postoperative complications were the significant risk factor for
delayed time to resume normal diet (p<0.001) and prolonged hospital
stay (p<0.001). Conclusion: Hypoalbuminemia is a potential predictor
of delayed recovery of bowel function postoperatively and significantly
associated with postoperative complications in right-sided colon cancer
patients undergone right hemicolectomy.
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